Norwegian study suggests that maternal use of acetaminophen during pregnancy may be associated with ADHD risk in offspring

A recent study in the journal Pediatrics showed a twofold higher rate of attention deficit hyperactivity disorder (ADHD) among offspring that were exposed to 29 days or more of maternal acetaminophen use during pregnancy. If maternal acetaminophen use was less than 8 days there was a lower rate of ADHD. Although maternal preconceptional acetaminophen use was not associated with ADHD, paternal preconceptional use did have a similar association between maternal use of acetaminophen during pregnancy and ADHD. The study had strengths but also did have some inherent limitations as most studies do, and in their conclusion, the authors stated that their study does not provide definitive evidence for or against a cause-and-effect relationship between maternal acetaminophen use and ADHD.