It has been well established that 20% of couples struggling to conceive solely have a male factor as the culprit with an additional 40% having a male factor contributing to the challenge along with a female factor, suggesting that 60% of the time there is male factor involvement. The other clear trend is that over the last 50 years there has been a decline in overall sperm counts and essentially a trend to poorer male fertility over time. This has prompted the need for higher levels of science, evaluations, and treatment options for infertile men. Dr. Kavoussi states, “In response to the need for fertility care for more and more men in more challenging scenarios the scientific community has made leaps and bounds in advancements for diagnoses and treatment of infertile men.” The current publication in which Dr. Kavoussi was a coauthor discusses such advancements including genetics, “omics” technology, oxidative stress, sperm DNA fragmentation, artificial intelligence, genetic engineering, stem cell therapies, and reconstructive surgeries. Although many of these scientific breakthroughs are not ready for prime-time clinical use yet, there is hope for many more options in the future with further research in these areas.
Read the full publication, The Renaissance of Male Infertility Management in the Golden Age of Andrologyation.